Undergraduates Present Research

Undergrad Present ResearchFifteen Kalamazoo College students joined three of their teachers (professors Dwight Williams, Santiago Salinas and Ellen Robertson)  to present research at the 2016 West Michigan Regional Undergraduate Science Research Conference (WMRUGS) in Grand Rapids, Michigan.

The annual conference provides undergraduate students with an opportunity to present their own research to a large and supportive group of professional scientists. K was well represented with sophomores, juniors, and seniors in attendance from both the Departments of Biology and Chemistry: Suma Alzouhayli ’17 (Chemistry and Biology), John Bailey ’17 (Chemistry), Christi Cho ’17 (Chemistry), Quinton Colwell ’17 (Chemistry), Rachel Fadler ’17 (Chemistry), Sarah Glass ’17 (Chemistry), Sharat S. Kamath ’19, Christina Keramidas ’18 (Chemistry and Biology), Cydney Martell ’19 (Chemistry), Garret Miller ’16 (Chemistry), Susmitha Narisetty ’19 (Biology), Darren Peel ’17 (Biology), Collin Steen ’17 (Chemistry), Myles Truss ’17 (Chemistry), Raoul Wadhwa ’17 (Chemistry and Computer Science). In addition to presenting their research, students heard a keynote address and research talks by undergraduate and graduate students from regional colleges and universities. This free event also provided undergraduate researchers the opportunity to interact face-to-face with graduate school recruiters and to learn more about future career opportunities.

There were 169 undergraduate posters presented at WMRUGS from students representing 17 different college and universities. Ten students from the Kalamazoo College Department of Chemistry, presented results of their research conducted under the mentorship of Kalamazoo College faculty that included Laura Furge, Regina Stevens-Truss, and Dwight Williams. Other students presented the results of their summer research projects conducted in laboratories at Indiana University and the University of Oregon. Students from the Department of Biology presented their findings from research conducted this past summer in laboratories at South Dakota State University and Michigan State University.

K Alumna Elected to ACS Director Post

Christina BodurowChristina C. Bodurow ’79, senior director of external sourcing in the medicines development unit at Eli Lilly & Co. (Indianapolis), has been elected the District II Director for the American Chemical Society for 2017-2019. District II includes counties in Michigan, Indiana, Ohio, Pennsylvania, Kentucky, Tennessee, West Virginia, Virginia and North Carolina. At K Christina majored in chemistry. She served in student government, participated on the Hornet tennis and swimming teams, and played in the Jazz Band. She studied abroad in Erlangen, Germany. Christina earned her Ph.D. in organic/organometallic chemistry at Princeton University (1984). After graduate school she began her career at Eli Lilly in the chemical process research division. She led the early phase development of a number of neuroscience medicines, including the global submissions of nine new chemical entities. Kalamazoo College congratulates Christina on her ACS election.

Summer Science Shared

Summer ScienceScientific inquiry takes no summer break at Kalamazoo College, and a culmination of the summer’s work occurred at the Dow Science Center Mini Poster Session (August 26). In the chemistry department alone some 17 students worked in the laboratories of five chemistry faculty–Professors Bartz, Furge, Smith, Stevens-Truss and Williams. Those students include first-years, sophomores, juniors and seniors, many of the latter working on their Senior Individualized Projects. The mini poster session included 12 presenters explaining the science they had conducted during the summer. Quinton Colwell ’17 (in the red tie) is pictured discussing his poster, titled “Molecular Dynamics and Real-Life Drug Metabolism.” Molecular dynamics is the study of real life systems using computer models and simulations. Colwell’s work involved a relatively novel technique,biased molecular dynamics, which, he wrote, “brings an additional layer to computer simulations relevant to bench-top experiments. It has the potential to be a game-changer.” In addition to Colwell, other presenters included Sarah Glass ’17, Myles Truss ’17, Shreya Bahl ’17, Suma Alzouhayli ’17, and Blake Beauchamp ’17.

K Joins WMed to help local students dream big and enter pipeline to health science careers

SC07417Kalamazoo College welcomes 24 local high school students to campus this week for Early Introductions to Health Careers Level II (EIH-II), a cooperative program between K and Western Michigan University Homer Stryker M.D. School of Medicine (WMed).

The program intends to foster biomedical science and health career aspirations for underrepresented minorities and disadvantaged high school students, grades 10-12, in Kalamazoo County. Students will participate in interactive-presentations, hands-on lab experiments, note-booking, and be exposed to physicians, health professionals in allied health, and basic scientists.

The program is designed to improve students problem solving and critical thinking skills and “help them dream a little bigger and have fun,” said Dawn DeLuca, Healthcare Career Pathways Coordinator, Office of Health Equity and Community Affairs. According to DeLuca, EIH-II is part of Kalamazoo County’s first pipeline educational initiative for health professions. It also includes EHI Level I, a program for elementary school students, and Kalamazoo Education Enrichment Pre-Med Summer Program (KEEPS), a program for students in their first two years of college.

SC07430Two Kalamazoo College students are involved in KEEPS, which aims to add to the development of current undergraduate students who are science majors and interested in pursuing health professional careers through their participation as mentors and teaching assistants. The K students and high school students will also spend time with current WMed students, which include eight K alumni.

Laura Furge, Ph.D., associate provost and Roger F. and Harriet G. Varney Professor of Chemistry at K is leading EIH-II students through numerous presentations and experiments in K’s Dow Science Center this week. Among students’ activities will be learning basic lab safety and practices, talking about sodas and calculating how much soda they drink, conducting extraction and HPLC experiments, learning about enzymes via “toothpickase” activity, looking at the structure of proteins through 3D printing, and hosting a notebook competition and poster tour in Dow.

SC07426“Pipeline, pre-professional and enrichment programs are an important strategy for addressing the educational achievement gaps and diversifying the health professions and shortage of underrepresented minorities in the health professions,” said DeLuca.

“We believe it may also contribute to reducing health disparities in students’ communities through their improved knowledge about health, social determinants of health, and active citizenship through service learning with community organizations.”

PUI Paragon

Kalamazoo College Chemistry Professor Laura FurgeLaura Furge, the Roger F. and Harriet G. Varney Professor of Chemistry, is a feature profile in a recent ASBMB Today, the professional development magazine of the American Society for Biochemistry and Molecular Biology. The article, titled “Working at a PUI,” focuses on the demands and rewards faculty face at “primarily undergraduate institutions.” Turns out rewards and demands may be so intertwined they’re indistinguishable.  For example, Furge’s academic wheelhouse is biochemistry, and yet she also teaches classes in organic chemistry and general chemistry and even a first-year writing seminar on cancer. The latter has become one of her favorite classes, a case in point of the demand-and-reward hybrid. Furge also notes that at PUIs the professor is the inter-generational “continuity of knowledge.” That vital function requires patience and broader skills on the part of the professor (demand) and makes a PUI professor-investigator-mentor like Furge the progenitor of generations of chemists and chemistry educators–think of Sarah in the Book of Genesis or Celeste in Edward P. Jones’ novel The Known World. That latter reference underscores another for Furge’s great strengths (one the PUI article misses): a fierce commitment to the liberal arts. The Known World was Kalamazoo College’s Summer Common Reading choice in 2007. Furge sits on the committee that selects these works. She also will begin her duties as associate provost at Kalamazoo College beginning July 1.

Professor Receives Lucasse Award for Teaching Excellence

K Professor of Chemistry Regina Stevens-Truss
K Professor of Chemistry Regina Stevens-Truss

Kalamazoo College’s highest teaching honor is the Florence J. Lucasse Lectureship, awarded to a K faculty member in recognition of outstanding classroom teaching. The 2015-16 Lucasse Lectureship recipient is Professor of Chemistry Regina Stevens-Truss. And for this honor, she gets to deliver a lecture! Hear this outstanding teacher talk about her love of teaching – and celebrate her award – Thursday May 19, 4:00-5:30 p.m., in the Olmsted Room of Mandelle Hall.

“I love what I do every day, and I wake up every day looking forward to it,” says Professor Stevens-Truss. “I get to learn with young people and share my love of learning with them. For now, life doesn’t get better than this.”

Professor Stevens-Truss is a medicinal biochemist who has taught at K since 2000. She previously taught at the College of Pharmacy, University of Michigan. Her teaching responsibilities at K include Antibiotics: Global Health and Social Justice, Introductory Chemistry II, Biochemistry, and Principles of Medicinal Chemistry. Her research focuses on understanding the enzyme nitric oxide synthase and its involvement in Alzheimers’ disease, research she enjoys carrying out with her students.

She has also been involved in numerous outreach programs that have taken her and her students into the Greater Kalamazoo community and bringing the community to the K campus. These have included Art & Science of Medicine, a summer workshop for high school students intending to pursue a career in medicine, and Sisters in Science, a K student group supporting young girls who demonstrate an aptitude for math and science.

She currently helps lead the Science and Social Justice Project, an initiative of the Arcus Center for Social Justice Leadership (ACSJL) at Kalamazoo College and the Division of Medical Sciences at Harvard Medical School. The Project aims to study and promote the value of social justice in scientific education and research, and to identify, connect, and coordinate scholars doing science and social justice teaching and research.

Professor Stevens-Truss recently helped coordinate a three-day “Science and Social Justice Think Tank” at the ACSJL attended by professors, scholars, scientists, public health and environmental leaders from across the country working at the intersection of science and social justice, as well as stakeholders in academic institutions and scientific organizations who can speak to diversity in the STEM fields and to the changing landscape of science and society.

Professor Stevens-Truss earned a B.A. degree at Rutgers University and a Ph.D. degree at University of Toledo. She is a married mother of two children who enjoys photography, bowling, watching sports (“especially those involving my kids”), and watching CSI.

The Florence J. Lucasse Lectureship (for outstanding classroom teaching) and Fellowship (for outstanding achievement in creative work, research or publication) at Kalamazoo College were established in 1979. The awards were created to honor Florence J. Lucasse, alumna of Kalamazoo College Class of 1910, in recognition of her long and distinguished career and in response to the major unrestricted endowment gift given to the college in her will.

Life’s Imperative: Social Justice in Science

Social Justice Conference AudienceA seed—call it science-and-social-justice—has been germinating in the mind of Regina Stevens-Truss since December of 2009. In truth, Stevens-Truss (the Kurt D. Kaufman Associate Professor of Chemistry) has been thinking on that matter long before then. But the occasion of that December seven years ago—a faculty workshop sponsored by the Arcus Center for Social Justice Leadership (ACSJL) on the topic of incorporating social justice into the undergraduate curriculum—and a conversation at the event with Harvard University professor Jonathan Beckwith (well known for uniting social justice and science in his science courses) gave Stevens-Truss a language for her thinking.

That small seed has come to fruition in several ways over the years, most recently (in a very big way) with the April 2016 Science and Social Justice Think Tank (SSJTT), which gathered from across the country some 60 experts and advocates for social justice consideration in the conduct of research and science education.

The SSJTT, like so many previous fruitions, was sponsored by the ACSJL. “It is so vital to have the social justice center here,” says Stevens-Truss. On the issue of science and social justice, as with so many others, the center provides “a language, a name, if you will, a platform for what needs to be done, and the national reach to do it,” says Stevens-Truss. Language, platform, reach. “The social justice center is indispensable.”

According to Stevens-Truss, in recent years scientists and science educators have improved in the area of science and ethics. Both groups have become better at considering and carefully answering questions like: am I doing research (or teaching research protocols) in a way that respects the human rights of research subjects as well as the integrity of the scientific process? Comparatively, science has been less effective in its consideration of social justice matters.

“We must become better at framing and answering social justice questions,” says Steven-Truss. Is the research we are considering good for society? Who will benefit? Will different communities benefit disproportionately? Will there be adverse burdens to bear and, if so, who or what communities are most likely to bear those burdens?

Social Justice Conference ParticipantsA similar battery of social justice questions for science educators certainly includes this one: What course content is required to ensure that students from various backgrounds see themselves as stakeholders in science to a degree that is sufficient to keep them involved in the discipline?

That last question inspired at least one living ancestor of April’s SSJTT. In 2011 Stevens-Truss, Beckwith and Lisa Brock, academic director of ACSJL and associate professor of history, began collecting the syllabi of science courses that integrate social justice. Two K undergraduate students and a Harvard graduate student searched colleges and universities across the country and compiled the various ways science professors fit social justice into the academic content of their courses. The trio made these ideas available as a resource to all on science and social justice website, part of ACSJL’s Praxis project.

Work on the SSJTT soon followed. Eliza Jane Reilly, deputy executive director of the National Center for Science and Civic Engagement; Karen Winkfield, radiation oncologist at the Massachusetts General Hospital Cancer Center, and Anne Dueweke, director of faculty grants and institutional research at K, joined Stevens-Truss, Beckwith and Brock to form a planning committee. Senior Shannon Haupt, an environmental activist and anthropology and sociology major, served as project assistant.

“We wanted to gather professors, scholars, scientists, public health and environmental leaders working where science and social justice intersect,” says Brock. “We also sought experts on diversity in the STEM fields and people thinking about changes underway in society and science.”

SSJTT participants engaged with three questions: What benefits will accrue when social justice is included in undergraduate, graduate and medical school science courses? What are specific strategies for integrating social justice issues into scientific research? What disciplinary and institution reforms will most effectively advance social-justice-in-science nationally?

“We need to train the next generation in a way that these questions are second nature,” says Stevens-Truss. Particularly gratifying for her was the liberal arts diversity of the SSJTT’s presenters and participants. Attendees included researchers, science professors, policy makers, lawyers, journalists, writers and philanthropists.

“Our evening keynote speakers were a writer [and English professor Debra Marquart, “Owning Our Future: A Poet’s Response to Extraction”] and a visual artist [Mary Beth Heffernan, “Ebola, Culture and Social Justice Through the Lens of a Photographer”],” says Stevens-Truss.

Such diversity matters a great deal, she added, because social justice connects to art, poetry, the social sciences and the hard sciences, a fact with “deep implications for how we teach and practice science.” The committee is currently tackling how to extend the SSJTT’s momentum. The Praxis Center will help. And the language, platform and reach of the ACSJL will be critical.

Stevens-Truss has long been an activist, albeit (perhaps) without the sobriquet. Her work on campus with Sukuma, locally with Sisters in Science, and nationally in a program that connects practicing scientists and middle school teachers comprise distinct expressions of her preoccupation with matters of social justice and science. And now, through the Praxis Center and programs like the SSJTT, the cause and (yes!) its activists have a growing magnitude and unity.

“As scientists and educators we must help each other see our impact on people,” says Stevens-Truss, “and on communities. Especially the marginalized people and communities who often are the most adversely affected by our choices in boardrooms, laboratories, classrooms and scientific funding committees.”

Heyl Earns Goldwater

Heyl Scholar Raoul WadhwaRaoul Wadhwa ’17 has won the very competitive and nationally prestigious Goldwater Scholarship. The Goldwater Scholarship Program was created to encourage outstanding students to pursue research careers in mathematics, the natural sciences, or engineering and to foster excellence in those fields.

Raoul will graduate in June 2017 with majors in chemistry and mathematics. At K he currently serves as the Civic Engagement Scholar for the Center for Civic Engagement’s Spanish Medical Interpreting group. He coordinates students from K to serve as medical translators for Spanish-speaking patients and English-speaking staff, nurses, and doctors at a local medical clinic. “I first participated in this program as a first-year,” says Raoul, “and I enjoy working with a group of fellow students to improve the health of our community.” He has yet to decide where he will attend graduate school, but he has no uncertainty over his decision regarding his undergraduate education. “I am really glad that I was able to attend K,” says the Heyl scholar. “The relatively small community size fosters the building of close relationship with classmates and colleagues, and I value that about K.” According to Diane Kiino, the College’s director of health sciences and community and global health, K’s last Goldwater Scholar (Tibin John ’15) also was a Heyl Scholar.

K at EB

Victoria Osorio '16 and Sarah Glass '17
Victoria Osorio ’16 and Sarah Glass ’17

Two Kalamazoo College chemistry majors, Victoria Osorio ’16 and Sarah Glass ’17, attended the annual Experimental Biology meeting in San Diego, Calif. Experimental Biology is a joint meeting of six different societies including the American Society for Biochemistry and Molecular Biology (ASBMB) as well as societies for physiology, nutrition, pharmacology, pathology, and anatomy. “The meeting is a great opportunity for students to present their work and attend a variety of engaging scientific talks,” says Laura Furge, the Roger F. and Harriet G. Varney Professor of Chemistry. “There were more than 15,000 scientists in attendance.”

Osorio and Glass presented results of their research as part of the Undergraduate Poster Competition and as part of the regular scientific session for ASBMB. Their presentations centered on recent work in the Furge lab with protein variants of an important human liver enzyme called CYP2D6. CYP2D6 helps the human body process drugs. The titles of the Osorio and Glass posters were, respectively, “Susceptibility of Four Human CYP2D6 Variants and One Active Site Mutant to Inhibition by the Mechanism-based Inactivator SCH 66712” and “Activity and Kinetic Characterization of Human CYP2D6 Polymorphisms with Bufuralol and Dextromethorphan.”

There were more than 225 undergraduate posters in the ASBMB competition from students across the country and from a variety of college and universities. One Grand Prize and four Honorable Mention awards were presented to students in each of the four research topic categories (proteins and enzymes / metabolism, bioenergetics, lipids and signal transduction / DNA, chromosomes, and gene regulation / cellular and developmental biology). Glass won an Honorable Mention for the “Proteins and Enzymes” category and was recognized the next day in front of an audience of hundreds of scientists, educators and students at the award lecture for outstanding contributions to education. Glass’s presentation was based on the culmination of nearly three years of research in the Furge lab; Glass will complete her SIP with Furge this summer and the lab hopes to publish the results later in 2016 along with co-author Osorio and other recent Furge lab research assistants.

After graduation, Osorio will enter the Post-baccalaureate Research Education Program at Case Western Reserve University. Glass will complete her degree in Fall 2016 (two terms early), and she plans to start graduate school in biochemistry or pharmacology in 2017.

Travel to ASBMB for Osorio and Glass was supported by a grant to Furge from the National Institutes of Health. Glass also received an ASBMB Travel Award of $500.

Next year’s Experimental Biology meeting will be in nearby Chicago, Illinois, says Furge, “and we hope to take a large group of students from the Departments of Chemistry and Biology.”

Diamonds in the Rough

Tom HigginsTom Higgins ’92 returned to his alma mater in early April as part of a visit coordinated by the Kalamazoo Section of the American Chemical Society. Higgins talked about “How Undergraduate Research Experiences Can Change Students’ Lives.” He should know.  Higgins and a number of collaborators have made great strides in cultivating future scientists by introducing undergraduate research experiences for students at two-year institutions. Known as STEM-ENGINES (Engaging the Next Generation in Exploring STEM), their research collaborative has enabled over 286 Chicago-area students, including many first-generation American citizens, to gain academic-year and summer research experience mentored by chemistry and biology faculty. Often these “diamonds in the rough” may not have envisioned research as a potential career path.

The K chemistry major cites his foreign study experience (Erlangen, Germany) as a source of insight and empathy into his own students’ discomfort in learning beyond their comfort zone. He sees community colleges as important part of the higher education landscape and his research demonstrates that small investments in a student can have a big payoff benefiting individuals, families, institutions, and communities.

Higgins is a program director in the National Science Foundation’s Division of Undergraduate Education, and he also serves as a professor at Harold Washington College, one of the City Colleges of Chicago.
He began teaching at Harold Washington in 1998 after completing his Ph.D. at Northwestern. He never thought he’d be there as long as he has been, but–as he told an audience of students and faculty from K, Western Michigan University and Kalamazoo Valley Community College– the atmosphere created by small class sizes made it hard to leave.

Text and photo by Ann Jenks