{"id":16862,"date":"2022-05-17T10:50:11","date_gmt":"2022-05-17T14:50:11","guid":{"rendered":"https:\/\/www.kzoo.edu\/news\/?p=16862"},"modified":"2022-05-17T10:52:22","modified_gmt":"2022-05-17T14:52:22","slug":"kalamazoo-lab","status":"publish","type":"post","link":"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/","title":{"rendered":"Biology Student Gains Skills, Perspective Working at Kalamazoo Lab"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab-600x338.jpg\" alt=\"Dwight Williams' lab at Dow Science Center\" class=\"wp-image-16865\" width=\"557\" height=\"314\" srcset=\"https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab-600x338.jpg 600w, https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab-300x169.jpg 300w, https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab-150x84.jpg 150w, https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab-1536x864.jpg 1536w, https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab.jpg 1600w\" sizes=\"auto, (max-width: 557px) 100vw, 557px\" \/><figcaption>Maddy Harding \u201922, third from left, was one of a group of K students performing research in<br>the lab of Roger F. and Harriet G. Varney Associate Professor of Chemistry Dwight Williams<br>last summer. Harding also holds a job at local lab Genemarkers, where she has assisted<br>in COVID-19 PCR testing. <\/figcaption><\/figure><\/div>\n\n\n\n<p>Almost two years ago, Maddy Harding \u201922 found both a way back to Kalamazoo and an inside perspective on the COVID-19 pandemic.&nbsp;<\/p>\n\n\n\n<p>After being sent home with the rest of the Kalamazoo College campus in spring 2020\u2014home for Harding being a tiny town in the middle of the Rocky Mountains in Colorado\u2014she returned to Kalamazoo about five months later, in July 2020.&nbsp;<\/p>\n\n\n\n<p>\u201cI didn\u2019t really have a plan, but I wanted to be back in Kalamazoo,\u201d Harding said. \u201cI had a roommate, so we found an apartment and looked for jobs.\u201d&nbsp;<\/p>\n\n\n\n<p>Harding quickly found a position with <a href=\"https:\/\/genemarkersllc.com\/about\/\" data-type=\"URL\" data-id=\"https:\/\/genemarkersllc.com\/about\/\">Genemarkers<\/a>, a genetic research lab in Kalamazoo that had pivoted in the spring from its previous focus on personalized medicine and product development to COVID testing.\u00a0\u00a0\u00a0<\/p>\n\n\n\n<p>A <a href=\"https:\/\/www.kzoo.edu\/academic\/programs\/biology\/\" data-type=\"URL\" data-id=\"https:\/\/www.kzoo.edu\/academic\/programs\/biology\/\">biology major<\/a> with a <a href=\"https:\/\/www.kzoo.edu\/academic\/programs\/psychology\/\" data-type=\"URL\" data-id=\"https:\/\/www.kzoo.edu\/academic\/programs\/psychology\/\">psychology minor<\/a> and <a href=\"https:\/\/www.kzoo.edu\/academic\/programs\/neuroscience\/\" data-type=\"URL\" data-id=\"https:\/\/www.kzoo.edu\/academic\/programs\/neuroscience\/\">neuroscience concentration<\/a>, Harding would attend virtual classes during the day before going into the lab to prepare COVID test samples for PCR testing.\u00a0<\/p>\n\n\n\n<p>\u201cI would go to work at 4 p.m. and stay until we finished, which some nights was 10 or 11 p.m.,\u201d Harding said. \u201cThe facilities test all day and then they send all their samples in and they want results the next day. All the samples come in between 4 and 6 p.m., cooler after cooler after cooler. We were at one point in the winter receiving 3,000-4,000 samples a day. There would be coolers stacked to the ceiling full of patient samples.\u201d&nbsp;<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy-Harding-holding-SIP-551x800.jpg\" alt=\"Maggie Harding '22, who has worked at Genemarkers lab, holding her Senior Integrated Project\" class=\"wp-image-16867\" width=\"538\" height=\"781\" srcset=\"https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy-Harding-holding-SIP-551x800.jpg 551w, https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy-Harding-holding-SIP-300x436.jpg 300w, https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy-Harding-holding-SIP-103x150.jpg 103w, https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy-Harding-holding-SIP-1058x1536.jpg 1058w, https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy-Harding-holding-SIP.jpg 1059w\" sizes=\"auto, (max-width: 538px) 100vw, 538px\" \/><figcaption>Maddy Harding \u201922 completed her Senior Integrated Project testing a drug that could<br>help protect against neurodegenerative diseases on roundworms. She has honed her<br>lab skills working for the local lab Genemarkers for the past two years. <\/figcaption><\/figure><\/div>\n\n\n\n<p>The lab worked to maintain a 24- to 48-hour turnaround time on all samples.&nbsp;<\/p>\n\n\n\n<p>\u201cWe were just trying to get through as many samples as possible in a short time while also being accurate and careful,\u201d Harding said. \u201cWe were in full PPE [personal protective equipment]\u2014scrubs, gown, shield, mask, two pairs of gloves. There were definitely stressful situations and a bit of fear, especially at the beginning, because that was before vaccines and I was touching COVID every single day. My coworkers are great, though, and I felt like I was making an impact on a lot of people. I\u2019m glad I was able to help in some way.\u201d&nbsp;<\/p>\n\n\n\n<p>Even as K returned to in-person classes and the schedule grew more challenging, the job offered Harding inside information on the state of the pandemic. Harding found it interesting to see how the number of samples and positivity rates fluctuated and to understand the PCR testing process.&nbsp;&nbsp;<\/p>\n\n\n\n<p>\u201cMy friends would always ask me for more details about what was actually going on,\u201d Harding said. \u201cI could tell them what pharmacies to go to at the peak times when our lab had one of the shortest turn-around times.\u201d&nbsp;<\/p>\n\n\n\n<p>At times, Genemarkers has provided COVID testing for various pharmacies, nursing homes, assisted living facilities and colleges, including K.&nbsp;<\/p>\n\n\n\n<p>\u201cThat was tough at times,\u201d Harding said. \u201cThe samples come with requisition forms that have the name and all the information for the patient. I would see people I sit next to in class, see their names on a COVID test. I don&#8217;t ever see the results with the name, and of course with HIPAA privacy laws I couldn&#8217;t say anything. Even though it\u2019s all confidential, it was an interesting dynamic to navigate.\u201d&nbsp;<\/p>\n\n\n\n<p>As the rate of testing has slowed, Harding has transitioned into a research-and-development role with Genemarkers, testing the efficacy and safety of various skin care products.&nbsp;<\/p>\n\n\n\n<p>Working at Genemarkers has taught Harding important lessons about working in a team, problem solving and working under pressure.&nbsp;<\/p>\n\n\n\n<p>The job has also boosted Harding\u2019s lab skills, which helped when working on her Senior Integrated Project, researching the neuroprotective effect of a drug targeting serotonin receptors in <em>C. elegans<\/em>, a type of roundworm.&nbsp;<\/p>\n\n\n\n<p>\u201cWe looked to see if the drug has neuroprotective effects and it did, so that was exciting,\u201d Harding said. \u201cWe did have some significant results. Neurodegenerative diseases are a big problem. There are a lot of different types and one of the problems in treating them is that they all have different mechanisms of action of neuronal death. A lot of treatments look at each one specifically. This research looked at them more collectively to see if there was more of a common process of cell death that is occurring in all of the different diseases.\u201d&nbsp;<\/p>\n\n\n\n<p>Although much more research is needed, Harding\u2019s work could eventually contribute to a potential treatment for neurodegenerative diseases.&nbsp;<\/p>\n\n\n\n<p>The Genemarkers position has also had connections to Harding\u2019s coursework at K. At the height of COVID testing, she had to keep a dream journal for a dreams and consciousness class and discovered that about half her dreams were stress dreams about working in the lab.&nbsp;<\/p>\n\n\n\n<p>\u201cRight now, I\u2019m in a genetics class and I\u2019m learning all the little details I was missing for understanding the actual science I was doing,\u201d Harding said. \u201cYes, I know I\u2019m isolating RNA and then amplifying that using PCR, but what does that actually mean on the microscopic level? I\u2019m learning that now in class so it\u2019s cool to more fully understand the work I\u2019ve been doing for so long. That\u2019s a fascinating intersection between school and work.\u201d&nbsp;<\/p>\n\n\n\n<p>Harding is currently applying for medical school and hoping to start that in fall 2023.&nbsp;<\/p>\n\n\n\n<p>\u201cI just accepted a job for a research technician position for next year, for my gap year, and I think the Genemarkers experience made me a competitive applicant because I\u2019ve worked there for so long and have learned a variety of useful skills,\u201d Harding said.&nbsp;<\/p>\n\n\n\n<p>The job, at Northwestern University Feinberg School of Medicine, involves research on mitochondrial function. After graduation, Harding will move to Chicago for the job. Many of Harding\u2019s K experiences will apply to the lab tech work.&nbsp;<\/p>\n\n\n\n<p>For example, she will be working with rodents, which she has done via psychology research during her time at K. Harding helped run a taste aversion learning trial which has possible implications for cancer patients who often develop aversions to certain foods during chemotherapy treatments.&nbsp;<\/p>\n\n\n\n<p>In addition, Harding took a topics class for seniors on neurodegenerative disorders in the fall that operated like a journal club.&nbsp;<\/p>\n\n\n\n<p>\u201cWe read different papers every single week and presented the findings of the scientific literature to the class,\u201d Harding said. \u201cI got exposed to a lot of cutting-edge techniques that are being used and now I\u2019ll be using them next year.\u201d&nbsp;<\/p>\n\n\n\n<p>Harding learned about the lab tech opportunity through a professor\u2019s connection to a K alumnus who works in the lab.&nbsp;<\/p>\n\n\n\n<p>\u201cIt will be cool to talk to him about K,\u201d Harding said. \u201cIt\u2019s always fun to meet K alumni outside of K in a different context. You share this niche experience because it is such a small school and has so many traditions.\u201d&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A job at a Kalamazoo lab through the COVID-19 pandemic has helped Maddy Harding &#8217;22 boost her science skills, benefiting her Senior Integrated Project.<\/p>\n","protected":false},"author":252,"featured_media":16865,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,231],"tags":[52],"post_formats":[],"class_list":["post-16862","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-students","tag-biology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\r\n<title>Student Gains Perspective, Skills Working at Lab - News and Events<\/title>\r\n<meta name=\"description\" content=\"A job at a Kalamazoo lab through the COVID-19 pandemic has helped Maddy Harding &#039;22 boost her science skills, benefiting her Senior Integrated Project.\" \/>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/\" \/>\r\n<meta property=\"og:locale\" content=\"en_US\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"Student Gains Perspective, Skills Working at Lab - News and Events\" \/>\r\n<meta property=\"og:description\" content=\"A job at a Kalamazoo lab through the COVID-19 pandemic has helped Maddy Harding &#039;22 boost her science skills, benefiting her Senior Integrated Project.\" \/>\r\n<meta property=\"og:url\" content=\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/\" \/>\r\n<meta property=\"og:site_name\" content=\"News and Events\" \/>\r\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/KalamazooCollege\" \/>\r\n<meta property=\"article:published_time\" content=\"2022-05-17T14:50:11+00:00\" \/>\r\n<meta property=\"article:modified_time\" content=\"2022-05-17T14:52:22+00:00\" \/>\r\n<meta property=\"og:image\" content=\"https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab.jpg\" \/>\r\n\t<meta property=\"og:image:width\" content=\"1600\" \/>\r\n\t<meta property=\"og:image:height\" content=\"900\" \/>\r\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\r\n<meta name=\"author\" content=\"Frances Czuk\" \/>\r\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\r\n<meta name=\"twitter:creator\" content=\"@kcollege\" \/>\r\n<meta name=\"twitter:site\" content=\"@kcollege\" \/>\r\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Frances Czuk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\r\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/\",\"url\":\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/\",\"name\":\"Student Gains Perspective, Skills Working at Lab - News and Events\",\"isPartOf\":{\"@id\":\"https:\/\/www.kzoo.edu\/news\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab.jpg\",\"datePublished\":\"2022-05-17T14:50:11+00:00\",\"dateModified\":\"2022-05-17T14:52:22+00:00\",\"author\":{\"@id\":\"https:\/\/www.kzoo.edu\/news\/#\/schema\/person\/cbf493b4705a88cb4a448e23e75e1c4f\"},\"description\":\"A job at a Kalamazoo lab through the COVID-19 pandemic has helped Maddy Harding '22 boost her science skills, benefiting her Senior Integrated Project.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/#primaryimage\",\"url\":\"https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab.jpg\",\"contentUrl\":\"https:\/\/www.kzoo.edu\/news\/files\/2022\/05\/Maddy_Harding_lab.jpg\",\"width\":1600,\"height\":900,\"caption\":\"Maddy Harding \u201922, third from left, was one of a group of K students performing research in the lab of Roger F. and Harriet G. 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aria-label=\"archive of category News Stories\" href=\"https:\/\/www.kzoo.edu\/news\/category\/news\/\" rel=\"category tag\">News Stories<\/a><a aria-label=\"archive of category Students\" href=\"https:\/\/www.kzoo.edu\/news\/category\/students\/\" rel=\"category tag\">Students<\/a>","tags_info":"<a href=\"https:\/\/www.kzoo.edu\/news\/tag\/biology\/\" rel=\"tag\">biology<\/a>","social_share_info":"<a data-share=\"facebook\" href=\"https:\/\/www.facebook.com\/sharer.php?u=https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/\" class=\"pl-facebook-share social-share-default pl-social-share\" target=\"_blank\"><i class=\"fab fa-facebook-f\" aria-hidden=\"true\"><\/i><\/a><a data-share=\"twitter\" href=\"https:\/\/twitter.com\/share?url=https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/\" class=\"pl-twiiter-share social-share-default pl-social-share\" target=\"_blank\"><i class=\"fab fa-twitter\" aria-hidden=\"true\"><\/i><\/a><a data-share=\"linkedin\" href=\"https:\/\/www.linkedin.com\/shareArticle?url=https:\/\/www.kzoo.edu\/news\/kalamazoo-lab\/\" class=\"pl-linkedin-share social-share-default pl-social-share\" target=\"_blank\"><i class=\"fab fa-linkedin-in\" aria-hidden=\"true\"><\/i><\/a>","wordExcerpt_info":"<p>A job at a Kalamazoo lab through the COVID-19 pandemic has helped Maddy Harding &#8217;22 boost her science skills, benefiting her Senior Integrated Project.<\/p>\n","comment_info":"No 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